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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NME2P1 All Species: 53.94
Human Site: T79 Identified Species: 91.28
UniProt: O60361 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60361 NP_001018146 137 15529 T79 G R V M L G E T N P A D S K P
Chimpanzee Pan troglodytes XP_001147407 308 33377 T250 G R V M L G E T N P A D S K P
Rhesus Macaque Macaca mulatta XP_001096144 240 26905 T182 G R V M L G E T N P A D S K P
Dog Lupus familis XP_533973 152 17223 T94 G R V M L G E T N P A D S K P
Cat Felis silvestris
Mouse Mus musculus Q01768 152 17345 T94 G R V M L G E T N P A D S K P
Rat Rattus norvegicus P19804 152 17264 T94 G R V M L G E T N P A D S K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515701 267 30034 T94 G R V M L G E T N P A D S K P
Chicken Gallus gallus O57535 153 17269 T95 G R V M L G E T N P A D S K P
Frog Xenopus laevis P70011 154 17484 T95 G R V M L G E T N P A D S K P
Zebra Danio Brachydanio rerio NP_571001 153 17215 T95 G R V M L G E T N P A D S K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08879 153 17151 T95 G R Q M L G A T N P A D S L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LAH8 237 25755 T177 G R K L I G A T D P Q K S E P
Baker's Yeast Sacchar. cerevisiae P36010 153 17148 T95 G R T I L G A T N P L G S A P
Red Bread Mold Neurospora crassa Q9UUY8 152 16882 T94 G R T I L G A T N P L A S A P
Conservation
Percent
Protein Identity: 100 43.5 49.5 73.6 N.A. 85.5 85.5 N.A. 47.1 81 75.9 77.1 N.A. 68.6 N.A. N.A. N.A.
Protein Similarity: 100 43.8 53.7 80.9 N.A. 87.5 87.5 N.A. 49.4 86.2 83.1 83 N.A. 76.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.4 51.6 54.6
Protein Similarity: N.A. N.A. N.A. 45.5 68.6 68.4
P-Site Identity: N.A. N.A. N.A. 46.6 60 60
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 29 0 0 0 79 8 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 79 0 0 0 % D
% Glu: 0 0 0 0 0 0 72 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 100 0 0 0 0 100 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 15 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 8 0 72 0 % K
% Leu: 0 0 0 8 93 0 0 0 0 0 15 0 0 8 0 % L
% Met: 0 0 0 79 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 100 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % S
% Thr: 0 0 15 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 72 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _